Glutathione (GSH) is a small protein found in cells and is a master antioxidant that enhances the utilization and recycling of other antioxidants. It comprises three amino acids: cysteine, glycine, and glutamate. You can find it in foods such as spinach, avocados, asparagus, okra, etc., although cooking and pasteurization diminish its levels significantly.
GSH’s value as a nutritional supplement derives from its role in synthesizing proteins in the body. These proteins perform many functions relating to the synthesis and repair of tissues. Although, its primary use is still an antioxidant that prevents or slows down the damage caused by free radicals. As numerous bodily functions can create free radicals, damage caused by it starts to add up, causing what is known as oxidative stress.
Heart disease, cancer, diabetes, arthritis, and other inflammatory conditions are all linked to oxidative stress that could be neutralized by an antioxidant. As we age, our body’s Glutathione level naturally declines. Although this can be produced in the body (endogenous antioxidant), supplementation and following healthy lifestyle practices are important. The body’s demand for glutathione increases in times of immense stress – illness, injury, or infection (such as a global pandemic).
Since it is involved in many biological processes – free radical neutralization, detoxification, vitamin C and E regeneration, etc. – IV therapy Glutathione can support the immune system, aid in healing, and recovery, while helping your skin glow. GSH demonstrates a protective role towards all cells (brain, heart, liver, kidneys, lungs, etc), supporting cancer treatment and reproductive health. It even manifested benefits in the treatment of COVID-19.
Aside from its influence on a couple of medical conditions, GSH level also affects the skin and apparent signs of aging. In a 2017 study, subjects supplemented with GSH showed a significant reduction in wrinkles and increased skin elasticity compared to placebo treatments. Another study on females with brown or dark brown skin established that it is safe and effective in lightening the skin. This was further supported by Duperray in a 2021 study validating the lightening of skin coupled with the reduction of facial dark spot size.
A novel wound dressing incorporated with GSH accelerated the healing process by 70%. Combined with copper ions, another study explored the antimicrobial and wound healing potential of glutathione against multidrug-resistant (MDR) bacterial infections, where it prevented postsurgical wound infections and aided in wound closure. These are just some of the many undergoing research regarding this antioxidant’s use and endless potential, GSH.